Cluster models of molecular motors: kinesin and myosin V
نویسندگان
چکیده
منابع مشابه
Kinesin and myosin: molecular motors with similar engines.
Structure determination of the catalytic domains of two members of the kinesin superfamily reveals that this class of molecular motor exhibits the same architecture as myosin and suggests that these microtubule- and actin-based motors arose from a common ancestor.
متن کاملKinesin motors as molecular machines.
Molecular motor proteins, fueled by energy from ATP hydrolysis, move along actin filaments or microtubules, performing work in the cell. The kinesin microtubule motors transport vesicles or organelles, assemble bipolar spindles or depolymerize microtubules, functioning in basic cellular processes. The mechanism by which motor proteins convert energy from ATP hydrolysis into work is likely to di...
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Cytoskeletal trafficking systems are becoming more complex at every turn. A new study reports that a yeast myosin V walks on only a select few actin filaments - those that are decorated with tropomyosin.
متن کاملMolecular motors: The natural economy of kinesin
Kinesin is a molecular-scale walking machine. New analyses of its mechanism indicate that each step along a microtubule consumes one ATP molecule, and that the binding and cleavage of ATP precede detachment of the molecule's 'feet'. Directional walking ensues if ATP processing occurs preferentially on one foot.
متن کاملMyosin-I molecular motors at a glance.
Myosin-I molecular motors are proposed to play various cellular roles related to membrane dynamics and trafficking. In this Cell Science at a Glance article and the accompanying poster, we review and illustrate the proposed cellular functions of metazoan myosin-I molecular motors by examining the structural, biochemical, mechanical and cell biological evidence for their proposed molecular roles...
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ژورنال
عنوان ژورنال: Computer Research and Modeling
سال: 2014
ISSN: 2076-7633,2077-6853
DOI: 10.20537/2076-7633-2014-6-5-747-760